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Updated: Dec 5, 2025

Non-invasive Assessment of Microvascular and Endothelial Function
Published on: January 29, 2013
Whole blood viscosity predicts nondipping circadian pattern in essential hypertension
Abdullah K Dolu1, Ahmet Korkmaz2, Harun Kundi3
1Department of Cardiology, İzmir Katip Çelebi University Ataturk Training and Research Hospital, Izmir, 35360, Turkey.
Abstract:
Aim: We aimed to investigate the association between whole blood viscosity (WBV) and nondipping pattern in patients with essential hypertension. Materials & methods: A total of consecutive 530 patients who had been evaluated by ambulatory blood pressure monitoring were included. WBV was estimated by using hematocrit and plasma total protein levels for both WBV in low shear rate (0.5 s-1) and WBV in high shear rate (208 s-1) according to the de Simone's formula. Results: In the multivariate analysis, low shear rate and high shear rate of WBV were associated independently with nondipping pattern in patients with essential hypertension. Conclusion: As a simple, inexpensive and noninvasive tool, WBV seems to be a significant predictor of nondipping hypertension.
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