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Updated: Dec 5, 2025
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Published on: September 22, 2023
Impact of sleep on female and male reproductive functions: a systematic review
Gabriela Caetano1, Inès Bozinovic2, Charlotte Dupont3
1APHP, Hôtel-Dieu, Centre du sommeil et de la vigilance, centre de référence narcolepsies et hypersomnies rares, service de pathologies professionnelles et environnementales, Paris, France.
Objective:
To evaluate the association of sleep parameters on female and male reproductive functions.
Design:
Systematic review.
Setting:
Not applicable.
Patient(S):
Female and male individuals, either healthy or infertile.
Intervention(S):
Relevant articles were identified according to the The Preferred Reporting Items for Systematic Reviews and Meta-analyses recommendations in the PubMed and EMBASE databases from January 1, 2000 to June 8, 2020.
Main Outcome Measure(S):
The association between sleep and ovary function, spermatic function, natural fertility, and in vitro fertilization (IVF) outcomes was assessed.
Result(S):
A total of 33 studies that looked at the association between sleep and either ovary function (n = 10), spermatic function (n = 12), natural fertility (n = 5), or IVF outcomes (n = 6) were included. Overall, female and male fertility, as well as IVF outcomes may be affected by short sleep duration, evening chronotype, or shift/night work schedules. However, the results were hardly comparable due to the heterogeneous study methodologies used.
Conclusion(S):
Sleep may be an original and innovative parameter to consider in the reproduction field. Further investigation is needed to elucidate how sleep and fertility are interrelated and how sleep might constitute a useful modifiable target in infertility management.
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