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Related Concept Videos

Amyloid Fibrils03:03

Amyloid Fibrils

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Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
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Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
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Related Experiment Video

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Novel Atomic Force Microscopy Based Biopanning for Isolation of Morphology Specific Reagents against TDP-43 Variants in Amyotrophic Lateral Sclerosis
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Curious case of FTD-ALS

K A Josephs1

  • 1Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA josephs.keith@mayo.edu.

Journal of Neurology, Neurosurgery, and Psychiatry
|October 15, 2020
PubMed
Summary

No abstract available in PubMed .

Keywords:
ALSbehavioural disordercognitive neuropsychologyfrontotemporal dementia

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