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A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Superficial epithelioma with sebaceous differentiation.
Superficial epithelioma with sebaceous differentiation (SESD) presents as solitary facial papules in older adults. This non-aggressive tumor shows sebaceous cell clusters and does not recur after simple excision.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Superficial epithelioma with sebaceous differentiation (SESD) is a rare skin tumor.
- Its histogenesis and clinical behavior require further elucidation.
Purpose of the Study:
- To report and characterize five cases of SESD.
- To describe the clinical and pathological features of SESD.
Main Methods:
- Case series reporting.
- Clinical and histopathological examination of five SESD tumors.
Main Results:
- Five solitary SESD papules were observed on the faces of patients aged 57-72.
- Tumors exhibited superficial, platelike proliferation with basaloid to squamoid cells and mature sebaceous cell clusters.
- No recurrences or metastasis were noted after simple excision.
Conclusions:
- SESD is a non-aggressive epithelial tumor with a tendency for sebaceous differentiation.
- Simple excision appears to be an effective treatment for SESD.
- Further research into the histogenesis of SESD is warranted.
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