Related Experiment Video
Updated: Dec 5, 2025

RNA-seq Analysis of Transcriptomes in Thrombin-treated and Control Human Pulmonary Microvascular Endothelial Cells
Published on: February 13, 2013
Transcriptome Sequencing Data Sets of Human Lung Epithelial Cells in the Course of Francisella tularensis Infection
Adi Bercovich-Kinori1, Ma'ayan Israeli2, Theodor Chitlaru2
1Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel adiki@iibr.gov.il.
Abstract:
Francisella tularensis is a highly infectious intracellular bacterium representing the causative agent of tularemia, a severe disease which requires prompt antibacterial intervention for mitigating its potential high mortality. Inhaled bacteria interact with lung cells belonging to various subpopulations, including those of the epithelium. As of today, the host epithelial response to inhalational infection with F. tularensis is poorly understood. Here, we announce host transcriptome data sets which systematically address the human epithelial response to F. tularensis at different time points postinfection.

