Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Rapidly Varying Flow

Rapidly Varying Flow

Rapidly varying flow (RVF) in open channels is characterized by abrupt changes in flow depth over a short distance, with the rate of depth change relative to distance often approaching unity. These flows are inherently complex due to their transient and multi-dimensional nature, making exact analysis difficult. However, approximate solutions using simplified models provide valuable insights into their behavior.Key Features of Rapidly Varying FlowRVF is commonly observed in scenarios involving...

Urodynamic Studies: Uroflowmetry

Urodynamic Studies: Uroflowmetry

Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...

Poiseuille's Law and Reynolds Number

Poiseuille's Law and Reynolds Number

Any fluid in a horizontal tube can flow due to pressure differences—fluid flows from high to low pressure. The flow rate (Q) is the ratio of pressure difference and resistance through a horizontal tube. The greater the pressure difference, the higher the flow rate. The flow resistance is expressed as:

The Buckingham Pi Theorem

The Buckingham Pi Theorem

The Buckingham Pi theorem provides a structured method to simplify fluid dynamics problems by reducing complex systems of variables to dimensionless terms.

Load-frequency control

Load-frequency control

Load-frequency control (LFC) is vital for maintaining power system stability, ensuring that frequency and power flows remain within acceptable limits during load changes. Turbine-governor control eliminates rotor accelerations and decelerations following load changes. However, a steady-state frequency error persists when the change in the turbine-governor reference setting is zero. In an interconnected power system, each area agrees to export or import a scheduled amount of power through...

Fast Decoupled and DC Powerflow

Fast Decoupled and DC Powerflow

The fast decoupled power flow method addresses contingencies in power system operations, such as generator outages or transmission line failures. This method provides quick power flow solutions, essential for real-time system adjustments. Fast decoupled power flow algorithms simplify the Jacobian matrix by neglecting certain elements, leading to two sets of decoupled equations:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Scalpel wielding sans data!: <i>The missing beat of Indian cardiothoracic surgical landscape</i>.

Indian journal of thoracic and cardiovascular surgery·2026

Same author

The EACTS Innovation Committee's Perspective on the "Heart Valve of the Future".

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026

Same author

Just to say goodbye…. ….one last hurrah!

Indian journal of thoracic and cardiovascular surgery·2026

Same author

Hypertrophic cardiomyopathy-an enigma unravelling.

Indian journal of thoracic and cardiovascular surgery·2026

Same author

Gender discourse - needle refuses to budge.

Indian journal of thoracic and cardiovascular surgery·2025

Same author

Diagnostic Challenge and Surgical Management of Accessory Mitral Valve Tissue.

Journal of cardiothoracic and vascular anesthesia·2025

Search research articles

Related Experiment Video

Updated: Dec 5, 2025

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats

Published on: June 28, 2019

Fractional flow reserve.

Om Prakash Yadava¹, Filip Casselman²

¹National Heart Institute, New Delhi, India.

Indian Journal of Thoracic and Cardiovascular Surgery

|October 16, 2020

Summary

Physiologically guided surgery improves outcomes for heart revascularization. The GRAFITTI Trial will assess if this approach benefits surgical myocardial revascularization, addressing a current evidence gap.

Area of Science:

Cardiovascular Surgery
Interventional Cardiology
Clinical Trials

Background:

Physiologically guided coronary revascularization demonstrates superior outcomes and resource utilization in percutaneous interventions.
The effectiveness of this approach in surgical myocardial revascularization remains largely uninvestigated.
A need exists to establish the evidence base for physiological guidance in surgical revascularization.

Purpose of the Study:

To evaluate the applicability and effectiveness of physiologically driven coronary revascularization in the context of surgical myocardial revascularization.
To address the current lack of evidence regarding physiological guidance in surgical revascularization procedures.
To present the rationale and design of the GRAFITTI Trial, investigating this specific clinical question.

Keywords:

Fractional flow reserve GRAFITTI Trial Revascularization

More Related Videos

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

Published on: August 9, 2024

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Published on: April 13, 2015

Related Experiment Videos

Last Updated: Dec 5, 2025

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats

Published on: June 28, 2019

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

Published on: August 9, 2024

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Published on: April 13, 2015

Main Methods:

The GRAFITTI Trial is designed to bridge the evidence gap concerning physiologically driven surgical myocardial revascularization.
The trial's rationale and design are discussed by Dr. F Casselman.
Specific methodologies for assessing physiological guidance in surgical revascularization will be detailed within the trial protocol.

Main Results:

Results are pending as the GRAFITTI Trial is designed to generate this evidence.
The study aims to provide data on outcomes and resource utilization for physiologically guided surgical revascularization.
This research will contribute novel insights into optimizing surgical myocardial revascularization strategies.

Conclusions:

The GRAFITTI Trial is crucial for establishing the role of physiological guidance in surgical myocardial revascularization.
Evidence from this trial could lead to improved patient outcomes and resource allocation in cardiac surgery.
This study addresses a critical knowledge gap in cardiovascular medicine.