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Brown tumor complicating end-stage kidney disease
1Department of Internal Medicine, Texas A&M Health Science Center, College of Medicine, Baylor University Medical Center, Dallas, TX, USA.
Clinical Nephrology. Case Studies
|October 16, 2020
Summary
Severe hyperparathyroidism (HPT) can cause destructive "brown tumors" in bone. This case highlights a young woman with chronic kidney disease (CKD) and secondary HPT who developed spinal cord compression from these rare lesions.
Area of Science:
- Endocrinology
- Nephrology
- Orthopedic Surgery
Background:
- Longstanding, severe hyperparathyroidism (HPT) can lead to rare bone complications.
- Brown tumors are locally destructive stromal masses, not true neoplasms, arising from advanced HPT.
- Secondary HPT (SHPT) is common in chronic kidney disease (CKD) patients on hemodialysis.
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