Is There any Relationship Between Granulomatous Mastitis and Seasons? An Analysis of Seasonal Frequency, Clinical,...

Idiopathic granulomatous mastitis (IGM) is a rare, resistant, and recurrent benign disease of the breast. IGM can be clinically and radiologically confused with breast carcinoma, and core needle biopsy is needed to diagnose. The etiology and pathogenesis of IGM have not been fully explained. This premenopausal disease may be associated with pregnancy, breastfeeding, autoimmune processes, inflammation, and oral contraceptives. However, there is no study on whether there is a seasonal relationship.

From January 2015 to January 2020, the seasonal relationship of IGM was evaluated in 37 females aged between 25-49.

Although all cases were distributed between September and May, there was no statistically significant result in the relationship with the season. US is the main modality in the diagnosis of this condition which only provides an accurate pre-diagnosis approach with the typical USG appearance features. Some MRI features may help us to distinguish IGM from breast malignities.

IGM is a rare chronic non-specific inflammatory lesion of the breast, which can be confused with benign and malignant breast diseases in both clinical and radiologic aspects. To understand the etiology of this condition better, the seasonal connection needs to be evaluated in larger patient groups.