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Updated: Dec 5, 2025

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety
Published on: November 11, 2022
Anxiety, depression, and stress in response to the coronavirus disease-19 pandemic
Héctor J Pérez-Cano1, Madeleine B Moreno-Murguía2, Oscar Morales-López1
1Centro de Investigación Biomédica, Fundación Hospital Nuestra Señora de la Luz, Mexico City, Mexico.
Objective:
The objective of the study was to determine the state of anxiety, depression, and stress present in the society during the development of the 2019 coronavirus pandemic.
Methods:
Mixed methods study; a three-section questionnaire was developed which included sociodemographic, perceptions, emotions, and behaviors related to the 2019 coronavirus pandemic, and two emotional assessment psychometric tests. The proportions and confidence intervals of the variables were calculated and compared using the Chi-square test.
Results:
More than 40% of the subjects presented some degree of anxiety and 41.3% depression; the proportion of stress was < 30%. Of the subjects who experienced anxiety, 18.6% also had moderate-to-very severe depression or stress.
Conclusion:
There are emotional indicators derived from the 2019 coronavirus pandemic in almost half of the study population. The identification and timely treatment of these states could lessen the psychological impact due to 2019 coronavirus.
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