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False-Positive 18F-PSMA-1007 and True-Negative 18F-Fluorocholine PET/CT Splenic Hemangioma
Emmanouil Panagiotidis1, Anna Paschali, Xanthi Xourgia
1From the PET/CT Department, Nuclear Medicine, "Theageneio" Cancer Center, Thessaloniki, Greece.
Abstract:
A 62-year-old man with prostate cancer underwent both F-PSMA-1007 and F-fluorocholine PET/CT studies for biochemical recurrence. F-PSMA-1007 PET/CT outperformed F-fluorocholine PET/CT in detecting lymph node metastases in the pelvis and retroperitoneum, whereas the former showed a focus of increased uptake in the spleen not seen on F-fluorocholine. The F-PSMA-1007 -avid lesion corresponded to a splenic hemangioma, which was initially detected in an MRI scan 10 years ago, unchanged in size. This case shows different features of F-PSMA-1007 and F-fluorocholine uptake, in an incidentally detected splenic hemangioma, alerting PET/CT reports for possible pitfall.
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