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Updated: Dec 5, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
In-House Anesthesia and Interventional Radiology Technologist Support Optimize Mechanical Thrombectomy Workflow after
Sudeepta Dandapat1, Sami Al Kasab1, Cynthia B Zevallos1
1Department of Neurology, University of Iowa Carver College of Medicine, Comprehensive Stroke Center, Iowa City, IA.
Mechanical thrombectomy (MT) after hours showed similar functional outcomes compared to during work hours. This suggests that 24-hour anesthesia and IR tech services may eliminate the negative impact of off-hours treatment for stroke patients.
Area of Science:
- Interventional Radiology
- Neuroendovascular Surgery
- Stroke Medicine
Background:
- Previous research indicates delayed treatment negatively impacts stroke patient outcomes.
- Mechanical thrombectomy (MT) is a critical intervention for acute ischemic stroke.
Purpose of the Study:
- To assess the effect of presentation time on MT metrics.
- To determine the association between time of presentation and long-term functional outcomes in an OR setting.
Main Methods:
- Retrospective analysis of 315 stroke patients undergoing MT (Jan 2015-Dec 2018).
- Comparison of outcomes between 'after-hours' (evenings, nights, weekends, holidays) and 'work hours' (weekdays 7 AM-5 PM).
- Primary outcome: 90-day modified Rankin Scale (mRS); Secondary outcomes: door-to-groin time, complications.
Main Results:
- 66.4% of MT procedures were performed after hours.
- No significant difference in 90-day mRS or functional independence (mRS 0-2) between after-hours and work hours groups.
- Door-to-groin times and procedural complication rates were similar between groups.
Conclusions:
- Mechanical thrombectomy during off-hours yielded comparable functional outcomes to procedures during work hours.
- The potential negative impact of after-hours treatment may be mitigated by 24-hour availability of anesthesia and IR technical support.
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