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Dissecting Host-virus Interaction in Lytic Replication of a Model Herpesvirus
Published on: October 7, 2011
ZIKV viral proteins and their roles in virus-host interactions
Moujian Guo1, Lixia Hui1, Yiwen Nie1
1State Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China.
Abstract:
The re-emergence of Zika virus (ZIKV) and its associated neonatal microcephaly and Guillain-Barré syndrome have led the World Health Organization to declare a global health emergency. Until today, many related studies have successively reported the role of various viral proteins of ZIKV in the process of ZIKV infection and pathogenicity. These studies have provided significant insights for the treatment and prevention of ZIKV infection. Here we review the current research advances in the functional characterization of the interactions between each ZIKV viral protein and its host factors.
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