Safety And Risk Factors For The Morbidity And Mortality Of Pneumonectomy: A Retrospective 10- Year Study In A Single...

Area of Science:

• Thoracic Surgery
• Surgical Outcomes
• Risk Factor Analysis

Background:

• Pneumonectomy, a major lung resection, is associated with significant post-operative morbidity and mortality.
• Identifying risk factors is crucial for improving patient selection and surgical outcomes.

Purpose of the Study:

• To assess the safety of pneumonectomy by identifying risk factors affecting post-operative outcomes.
• To evaluate the impact of preoperative variables on mortality and complication rates.

Main Methods:

• Retrospective study of 63 patients undergoing pneumonectomy between February 2008 and February 2018.
• Assessment of variables including age, gender, side of intervention, diagnosis, symptoms, substance abuse, and comorbidities.
• Analysis of early/late post-operative complications and death using SPSS statistics.

Main Results:

• Surgery-related mortality was 9.8%, with a 1-year survival rate of 76.2%.
• Early complications occurred in 35% of patients; late complications in 17.4%.
• Right-sided pneumonectomies showed a higher mortality risk; no other significant risk factors were identified.

Conclusions:

• Pneumonectomy is feasible for patients with adequate cardiopulmonary function, irrespective of age.
• Right-sided pneumonectomies increase post-operative death risk; neoadjuvant therapy warrants caution.
• Smoking cessation pre-surgery is recommended to mitigate complication risks.