Newborn Screening for CF across the Globe-Where Is It Worthwhile?
Virginie Scotet1, Hector Gutierrez2, Philip M Farrell3
1Inserm, University of Brest, EFS, UMR 1078, GGB, F-29200 Brest, France.
International Journal of Neonatal Screening
|October 19, 2020
Summary
Newborn screening for cystic fibrosis (CF) has transformed diagnosis and improved lives. This analysis provides a framework for regions considering CF newborn screening to determine where it is worthwhile.
Area of Science:
- Medical Genetics
- Public Health
- Pediatrics
Background:
- Newborn screening for cystic fibrosis (CF) has been implemented for decades, significantly improving patient outcomes.
- The decision to implement CF newborn screening involves careful consideration of benefits, risks, costs, and challenges.
Purpose of the Study:
- To analyze global data and factors influencing the decision-making process for implementing newborn screening for cystic fibrosis (CF).
- To provide an analytical framework for regions contemplating CF newborn screening programs.
Main Methods:
- Worldwide data analysis on the implementation of CF newborn screening programs.
- Evaluation of factors such as benefits, risks, costs, and policy considerations.
Main Results:
- Continued implementation of CF newborn screening programs by regions that have introduced them suggests perceived value.
- Lessons learned from established programs offer insights for new implementations.
Conclusions:
- Early diagnosis through CF newborn screening is considered worthwhile by public health and clinical leaders.
- An analytical framework and lessons learned are crucial for successful CF NBS implementation in new regions.
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