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Published on: July 29, 2021
Fatal Sodium Nitrite Poisoning: Key Considerations for Prehospital Providers
Matthew R Neth1, Jennifer S Love1, B Zane Horowitz1
1Received July 3, 2020 from Department of Emergency Medicine, Oregon Health & Science University, Portland, Oregon, USA (MRN, JSL, BZH, MRD); Tualatin Valley Fire & Rescue, Tigard, Oregon, USA (MRN, MRD); Oregon-Alaska Poison Center, Portland, Oregon, USA (JSL, BZH); Providence St. Vincent Medical Center, Portland, Oregon, USA (MDS); Washington County Emergency Medical Services, Hillsboro, Oregon, USA (RS). Revision received October 8, 2020; accepted for publication October 12, 2020.
Sodium nitrite overdose is a serious medical emergency causing severe hypotension and oxygen transport issues. This case highlights a fatal intentional overdose, emphasizing the need for rapid recognition and intervention by EMS.
Area of Science:
- Toxicology
- Emergency Medicine
- Cardiovascular Physiology
Background:
- Sodium nitrite is a potent oxidizing agent.
- It causes methemoglobinemia, leading to hypotension and impaired oxygen delivery.
- Most reported cases involve unintentional exposure.
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