Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

6.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
6.7K
Genetic Screens02:46

Genetic Screens

5.4K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
5.4K
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes02:16

Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

14.8K
The present-day mitochondrial and chloroplast genomes have retained some of the characteristics of their ancestral prokaryotes and also have acquired new attributes during their evolution within eukaryotic cells. Like prokaryotic genomes, mitochondrial and chloroplast genomes neither bind with histone-like proteins nor show complex packaging into chromosome-like structures, as observed in eukaryotes. Unlike mitotic cell divisions observed in eukaryotic cells, mitochondria and chloroplasts...
14.8K
Cis-regulatory Sequences02:02

Cis-regulatory Sequences

11.3K
Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
11.3K
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

352
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
352
Genomics02:02

Genomics

39.1K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
39.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A novel adomavirus from proliferative skin lesions of a broadnose sevengill shark (Notorynchus cepedianus).

Npj viruses·2026
Same author

A Single Cell Atlas of the Newt Iris During Lens Regeneration.

bioRxiv : the preprint server for biology·2026
Same author

Ceftriaxone to Prevent Early-Onset Pneumonia in Comatose Patients Following Out-of-Hospital Cardiac Arrest: A Pilot Randomized Controlled Trial and Resistome Assessment (PROTECT).

Chest·2025
Same author

Protein arginine methyltransferase 5 sustains Tip60-EP400 complex via SRSF1 in Merkel cell carcinoma.

Life science alliance·2025
Same author

Geographical, Ecological, and Genetic Drivers of Gut Microbial Diversity in Native and Invasive Minnows (Leuciscidae: Cyprinella).

Molecular ecology·2025
Same author

Fundamental questions in meiofauna research highlight how small but ubiquitous animals can improve our understanding of Nature.

Communications biology·2025
Same journal

Tracking Synthetic Adhesins on Bacterial Surfaces with Immunofluorescence Microscopy.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Post-Selection Methods for Analyzing mRNA Display Selections and Optimization of Hits.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

High-Performance Computing in Tandem Mass Spectrometry (MS/MS) Peptide Identification.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Engineering and Adapting Disulfide-Containing Proteins to Enable Intracellular Functionality.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

AI-Driven Protein Research: From Prediction to Design.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Methods for the In Vitro Selection of Protein and Peptide Libraries Using mRNA Display.

Methods in molecular biology (Clifton, N.J.)·2026
See all related articles

Related Experiment Video

Updated: Dec 5, 2025

In Vivo Modeling of the Morbid Human Genome using Danio rerio
12:31

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

21.1K

A Bioinformatics Tutorial for Comparative Development Genomics in Diverse Meiofauna.

Joseph L Sevigny1, Jon L Norenburg2, Francesca Leasi3

  • 1Hubbard Center for Genome Studies, Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH, USA.

Methods in Molecular Biology (Clifton, N.J.)
|October 19, 2020
PubMed
Summary
This summary is machine-generated.

This study presents a bioinformatics tutorial for analyzing meiofauna genomes, aiding in understanding miniaturization and evolutionary adaptations in these unique aquatic animals.

Keywords:
BioinformaticsConvergent evolutionGene architectureGene functionGenomicsHox genesInterstitial habitatMeiofaunaMiniaturization

More Related Videos

Transcriptomic Analysis of C. elegans RNA Sequencing Data Through the Tuxedo Suite on the Galaxy Project
10:19

Transcriptomic Analysis of C. elegans RNA Sequencing Data Through the Tuxedo Suite on the Galaxy Project

Published on: April 8, 2017

17.9K
Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
10:41

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Published on: May 9, 2017

9.5K

Related Experiment Videos

Last Updated: Dec 5, 2025

In Vivo Modeling of the Morbid Human Genome using Danio rerio
12:31

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

21.1K
Transcriptomic Analysis of C. elegans RNA Sequencing Data Through the Tuxedo Suite on the Galaxy Project
10:19

Transcriptomic Analysis of C. elegans RNA Sequencing Data Through the Tuxedo Suite on the Galaxy Project

Published on: April 8, 2017

17.9K
Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
10:41

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Published on: May 9, 2017

9.5K

Area of Science:

  • Marine Biology
  • Evolutionary Biology
  • Genomics

Background:

  • Miniaturization is a common evolutionary adaptation observed across diverse animal taxa.
  • Meiofauna, small invertebrates inhabiting aquatic interstitial spaces, exhibit extreme phyletic diversity and unique adaptations.
  • Understanding meiofaunal genome structure is crucial for insights into ancestral phenotypes and the evolution of miniaturization.

Purpose of the Study:

  • To provide a practical bioinformatics tutorial for genome analysis in meiofauna.
  • To enable genome assembly, comparison, and Hox cluster characterization in meiofaunal species.
  • To facilitate research into the genetic basis of miniaturization and adaptation in meiofauna.

Main Methods:

  • Genome assembly using bioinformatics pipelines.
  • Comparative genomics approaches for inter-species analysis.
  • Identification and characterization of Hox gene clusters.

Main Results:

  • Demonstration of a reproducible bioinformatics workflow for meiofauna genomics.
  • Characterization of Hox cluster organization in selected meiofaunal species.
  • Establishment of a framework for future genomic studies in meiofauna.

Conclusions:

  • The presented bioinformatics tutorial offers a valuable resource for meiofauna research.
  • Genome analysis provides insights into the evolutionary mechanisms driving miniaturization.
  • This work supports further exploration of meiofaunal biodiversity and evolutionary history.