Related Experiment Video
Updated: Dec 5, 2025

Assessment of Bone Fracture Healing Using Micro-Computed Tomography
Published on: December 9, 2022
Improved Detection of Scaphoid Fractures with High-Resolution Peripheral Quantitative CT Compared with Conventional
A M Daniels1,2, M S A M Bevers3, S Sassen1
1Departments of Surgery (A.M.D. and H.M.J.J.), Radiology (S.S.), Internal Medicine (C.E.W. and J.P.v.d.B.), and Orthopedic Surgery (S.K.), VieCuri Medical Centre, Venlo, the Netherlands.
High-resolution peripheral quantitative CT (HR-pQCT) detected 60% more scaphoid fractures than conventional CT. This advanced imaging technique improves diagnosis for suspected scaphoid fractures, reducing missed injuries.
Area of Science:
- Radiology
- Orthopedic Imaging
- Medical Diagnostics
Background:
- Conventional imaging (CT, MRI, bone scintigraphy) lacks a definitive reference standard for scaphoid fracture diagnosis.
- Diagnostic performance varies among current imaging techniques for suspected scaphoid fractures.
Purpose of the Study:
- To evaluate if high-resolution peripheral quantitative CT (HR-pQCT) improves scaphoid fracture detection compared to conventional CT.
- To assess the diagnostic accuracy of HR-pQCT in patients with clinically suspected scaphoid fractures.
Main Methods:
- 91 patients with suspected scaphoid fractures underwent clinical reassessment, conventional CT, and HR-pQCT.
- Fracture type (Herbert classification) and location correlation between CT and HR-pQCT were analyzed using Kendall W statistic.
Main Results:
- HR-pQCT identified scaphoid fractures in 26% of patients, versus 16% with conventional CT.
- High correlation (W=0.793) for fracture type and very high correlation (W=0.955) for fracture location between CT and HR-pQCT.
- 60% more scaphoid fractures were diagnosed using HR-pQCT.
Conclusions:
- HR-pQCT significantly increases scaphoid fracture detection rates compared to conventional CT.
- Conventional CT may miss a substantial proportion of scaphoid fractures, potentially over one-third in this study.
- HR-pQCT offers improved diagnostic performance for suspected scaphoid fractures.
Related Concept Videos
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Imaging Studies for Cardiovascular System V: CT
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

