NASA GeneLab: interfaces for the exploration of space omics data.

Area of Science:

• Space biology
• Systems biology
• Genomics

Background:

• NASA's GeneLab database collects omics data from spaceflight and simulated space stressors.
• This data aids in understanding molecular responses to space environments.

Purpose of the Study:

• To review GeneLab platform components, including a new data repository interface and GEODE web portal.
• To introduce a new GeneLab Application Programming Interface (API) for omics data visualization.
• To discuss outreach efforts for data utilization and hypothesis generation.

Main Methods:

• Review of GeneLab platform components: data repository, GEODE, and API.
• Discussion of GEODE's design for improved metadata accuracy.
• Overview of outreach initiatives and training programs.

Main Results:

• The GeneLab platform provides access to a comprehensive collection of space omics data.
• GEODE is designed to enhance data accuracy and reduce curation workload.
• A new API facilitates the visualization of processed omics data.

Conclusions:

• GeneLab is a valuable resource for systems biology approaches to spaceflight research.
• Enhanced data accessibility and new tools support novel discoveries.
• Outreach programs and training foster broader utilization of space omics data for human space exploration risk management.