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Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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The Tumor Microenvironment02:17

The Tumor Microenvironment

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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Combination Therapies and Personalized Medicine02:50

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
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Mitogens and the Cell Cycle02:38

Mitogens and the Cell Cycle

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Mitogens and their receptors play a crucial role in controlling the progression of the cell cycle. However, the loss of mitogenic control over cell division leads to tumor formation. Therefore, mitogens and mitogen receptors play an important role in cancer research. For instance, the epidermal growth factor (EGF) - a type of mitogen and its transmembrane receptor (EGFR), decides the fate of the cell's proliferation. When EGF binds to EGFR, a member of the ErbB family of tyrosine kinase...
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Updated: Dec 5, 2025

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
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A Tripeptide-Stabilized Nanoemulsion of Oleic Acid

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Multifunctional peptides for tumor therapy.

Ke Li1, Chuan-Jun Liu1, Xian-Zheng Zhang1

  • 1Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Wuhan University, Wuhan 430072, PR China.

Advanced Drug Delivery Reviews
|October 20, 2020
PubMed
Summary
This summary is machine-generated.

This review explores peptide-based nanomaterials for advanced tumor therapy. Integrating peptides enhances nano-systems for targeted drug delivery and improved functionality, overcoming peptide degradation challenges.

Keywords:
Drug deliveryPeptideStimulus-responsiveTargetingTumor therapy

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Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
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Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Oncology

Background:

  • Peptides offer diverse physiological functions valuable for anti-tumor applications.
  • Integrating peptides into nanomaterials enhances drug delivery systems.
  • Peptide integration addresses in vivo degradation and improves nano-system intelligence.

Purpose of the Study:

  • To review functional peptides with targeting and stimulus-responsive properties.
  • To outline recent developments in peptide-based multifunctional nanomaterials for tumor therapy.

Main Methods:

  • Literature review of peptide-based nanomaterials.
  • Analysis of targeting and stimulus-responsive peptide functionalities.
  • Summary of recent advancements in nanomaterial design for oncology.

Main Results:

  • Peptide integration into nanomaterials offers synergistic benefits.
  • Enhanced nano-systems exhibit improved targeting and responsiveness for cancer treatment.
  • Recent developments focus on multifunctional peptide-based materials.

Conclusions:

  • Peptide-based nanomaterials represent a promising strategy for advanced tumor therapy.
  • These systems offer enhanced drug delivery, targeting, and responsiveness.
  • Further research into peptide-nanomaterial integration will drive innovation in cancer treatment.