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Related Experiment Videos

Microcystic meningiomas.

G S Rutherfoord1, G Marus

  • 1Department of Pathology, University of Cape Town, South Africa.

Clinical Neuropathology
|July 1, 1987
PubMed
Summary
This summary is machine-generated.

Microcystic meningioma, a rare variant, can be misdiagnosed. Careful histological review, including ultrastructural analysis and glial fibrillary acidic protein (GFAP) absence, confirms this curable tumor.

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Area of Science:

  • Neuropathology
  • Surgical Oncology

Background:

  • Meningiomas are common primary brain tumors.
  • Accurate intraoperative diagnosis is crucial for patient management.

Observation:

  • Four patients presented with tumors exhibiting typical meningioma features.
  • Intraoperative frozen section diagnosis was incorrect in two cases.
  • Surgeons' clinical suspicion led to complete tumor resection.

Findings:

  • Subsequent histology confirmed microcystic meningioma.
  • Presence of meningothelial cellular whorls aided diagnosis.
  • Ultrastructural examination and GFAP absence were definitive.

Implications:

  • Awareness of microcystic meningioma variants is essential for pathologists.
  • Close collaboration between neurosurgeons and pathologists prevents misdiagnosis.
  • Timely and accurate diagnosis ensures appropriate treatment for this curable tumor.