Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Methods of Classification and Identification01:28

Methods of Classification and Identification

749
Bacterial identification relies on a diverse array of techniques to classify and understand microorganisms, each tailored to uncover specific characteristics. Traditional morphological approaches, while still valuable, are limited for closely related or structurally simple organisms. Modern methods integrate biochemical, serological, genetic, and advanced molecular tools to achieve greater accuracy.Morphological and Biochemical TechniquesMorphological characteristics, such as cell shape and...
749

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A CRISPRi-dCas9 System for Archaea and Its Use To Examine Gene Function during Nitrogen Fixation by Methanosarcina acetivorans.

Applied and environmental microbiology·2020
See all related articles

Related Experiment Video

Updated: Dec 5, 2025

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
08:48

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

Published on: February 16, 2022

3.2K

COVID-19: molecular and serological detection methods.

Ahmed E Dhamad1,2, Muna A Abdal Rhida1,2

  • 1Cell and Molecular Biology, University of Arkansas at Fayetteville, Fayetteville, AR, USA.

Peerj
|October 21, 2020
PubMed
Summary

Early detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial for controlling COVID-19. This review highlights the pros and cons of molecular and serological diagnostic methods for SARS-CoV-2.

Keywords:
COVID-19CRISPR-Cas12ELISAID NOW COVID-19Isothermal amplificationLFASARS-CoV-2rRT-PCR

More Related Videos

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.6K
Detection of SARS-CoV-2 Receptor-Binding Domain Antibody using a HiBiT-Based Bioreporter
07:44

Detection of SARS-CoV-2 Receptor-Binding Domain Antibody using a HiBiT-Based Bioreporter

Published on: August 12, 2021

3.4K

Related Experiment Videos

Last Updated: Dec 5, 2025

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
08:48

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

Published on: February 16, 2022

3.2K
Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.6K
Detection of SARS-CoV-2 Receptor-Binding Domain Antibody using a HiBiT-Based Bioreporter
07:44

Detection of SARS-CoV-2 Receptor-Binding Domain Antibody using a HiBiT-Based Bioreporter

Published on: August 12, 2021

3.4K

Area of Science:

  • Virology
  • Infectious Diseases
  • Diagnostic Technologies

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, necessitates effective diagnostic strategies.
  • SARS-CoV-2, a +ssRNA virus, spreads via respiratory droplets and direct contact.
  • Early detection is vital for reducing COVID-19 incidence and mortality.

Purpose of the Study:

  • To review current knowledge on COVID-19 detection methods.
  • To highlight the advantages and disadvantages of molecular and serological approaches.
  • To aid in selecting appropriate diagnostic tools for SARS-CoV-2.

Main Methods:

  • Review of existing literature on COVID-19 diagnostic techniques.
  • Comparison of molecular methods, including the gold standard rRT-PCR.
  • Evaluation of serological methods for SARS-CoV-2 detection.

Main Results:

  • Reverse transcription-quantitative polymerase chain reaction (rRT-PCR) is the established gold standard for SARS-CoV-2 detection.
  • Molecular methods offer high accuracy for early viral detection.
  • Serological methods demonstrate limitations in early detection and accuracy.

Conclusions:

  • Selecting the optimal COVID-19 diagnostic method presents challenges.
  • Molecular diagnostics are superior for early and accurate SARS-CoV-2 identification.
  • Further development and validation of diagnostic tools are essential.