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Aortic Ring Assay
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Hot Aortic Nodules

Erik Soule1, Quoc-Han Nguyen1, Mario Dervishi1

  • 1Interventional Radiology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.

Cureus
|October 21, 2020
PubMed

Insights

Positron emission tomography can detect 18-fluorodeoxyglucose uptake in atherosclerotic plaques. This finding may help identify high-risk patients for cardiovascular disease, enabling early intervention.

Area of Science:

  • Cardiovascular Medicine
  • Nuclear Medicine
  • Radiology

Background:

  • Atherosclerotic cardiovascular disease (ASCVD) is a major global health concern, leading to severe thrombotic complications like stroke and heart attack.
  • Early identification of aggressive ASCVD is crucial for effective risk stratification and treatment planning.

Observation:

  • This report details four patients where 18-fluorodeoxyglucose (FDG) uptake was observed in atherosclerotic plaques during positron emission tomography (PET) scans.
  • These PET scans were initially performed for indications unrelated to atherosclerosis detection.

Findings:

  • The study highlights the potential for FDG-avid atherosclerotic plaques to be incidentally discovered via PET imaging.
  • This incidental finding suggests a potential imaging biomarker for active or high-risk atherosclerosis.

Implications:

  • Detecting FDG-avid plaques could facilitate earlier diagnosis and intervention for ASCVD.
  • This may lead to improved patient outcomes through intensified lifestyle changes, medication, or procedures like endovascular atherectomy.

Keywords:
atherosclerotic cardiovascular diseasecerebrovascular accident (stroke)fluorodeoxyglucose positron emission tomographyinflammatory plaquesmyocardial infarctionplaque rupture

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