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High-throughput Screening for Protein-based Inheritance in S. cerevisiae
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Inheritance as Evolved and Evolving Physiological Processes.

Francesca Merlin1, Livio Riboli-Sasco2,3

  • 1IHPST-Université Paris 1 Panthéon-Sorbonne & CNRS, 13 rue du Four, 75006, Paris, France. francesca.merlin@univ-paris1.fr.

Acta Biotheoretica
|October 21, 2020
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Summary
This summary is machine-generated.

Biological transmission is viewed through a physiological lens, focusing on diverse mechanisms. This perspective highlights how these evolved processes are crucial for inheritance and evolution across generations.

Keywords:
Evolutionary dynamicsExtended inheritanceInheritanceNon-genetic transmissionPhysiological perspectiveStrategy of endogenizationTransmission mechanisms

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Area of Science:

  • Evolutionary Biology
  • Physiology
  • Genetics

Background:

  • Traditional studies of biological transmission often focus on transmitted factors (genes, etc.).
  • A physiological perspective offers a complementary view by examining the mechanisms facilitating transmission.

Purpose of the Study:

  • To provide an overview of biological transmission diversity from a physiological standpoint.
  • To analyze transmission mechanisms, considering their structural, dynamical, and functional aspects.
  • To understand what is transmitted across generations, how, and why.

Main Methods:

  • Adopting a physiological perspective to analyze biological transmission.
  • Examining transmission mechanisms across organisms' life cycles.
  • Integrating structural, dynamical, and functional features of these mechanisms.

Main Results:

  • Biological transmission is conceptualized as networks of heterogeneous physiological mechanisms.
  • These mechanisms are not limited to direct transmission pathways.
  • Transmission mechanisms are identified as key elements in evolutionary processes.

Conclusions:

  • Transmission mechanisms are both necessary for and a result of evolution.
  • A strategy of endogenization is proposed to view transmission and inheritance as evolved physiological mechanisms.
  • This approach emphasizes the dynamic and evolved nature of biological inheritance.