The LOCalizer Radiofrequency Identification System: An Effective New Technology for Localizing Non-Palpable Breast...

Area of Science:

• Oncology
• Surgical Oncology
• Medical Devices

Background:

• Breast cancer screening reduces morbidity and mortality by detecting early-stage, non-palpable tumors.
• Accurate localization of non-palpable tumors is crucial for successful breast-conserving surgery.
• Traditional wire-guided localization poses challenges in precise tumor targeting.

Purpose of the Study:

• To assess the feasibility and outcomes of a novel radiofrequency identification (RFID) system, LOCalizer, as an alternative to wire-guided localization.
• To evaluate the efficacy and safety of the LOCalizer RFID system in breast-conserving surgery.
• To determine the re-excision rates and complication profile associated with the LOCalizer system.

Main Methods:

• A prospective feasibility study was conducted between July 2019 and March 2020.
• Patients undergoing breast-conserving surgery had a LOCalizer RFID tag placed preoperatively.
• Surgical removal of the index lesion was guided by a handheld LOCalizer probe; tag retrieval and re-excision rates were primary outcomes.

Main Results:

• Sixty-nine patients (aged 50-69) underwent RFID tag insertion.
• All RFID tags were successfully placed and retrieved with the index lesion, with no migration observed.
• The overall re-excision rate was 17.4% due to positive radial margins; the complication rate was 1.4%.

Conclusions:

• The LOCalizer RFID system is an effective and safe wire-free localization method for non-palpable breast lesions.
• This technology offers a viable alternative to traditional wire-guided localization, potentially improving surgical outcomes.
• Further research may explore wider adoption and long-term efficacy of RFID-guided breast tumor localization.