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Microfluidic devices powered by integrated elasto-magnetic pumps.

Jacob L Binsley1, Elizabeth L Martin1, Thomas O Myers2

  • 1Department of Physics and Astronomy, University of Exeter, Physics Building, Stocker Road, Exeter, EX4 4QL, UK. jb778@exeter.ac.uk.

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|October 23, 2020
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Summary
This summary is machine-generated.

This study introduces an integrated elasto-magnetic pump for lab-on-a-chip devices, offering tuneable flow rates up to 600 microL/h. The novel system uses oscillating magnetic fields and allows for flow reversal, simplifying microfluidic applications.

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Area of Science:

  • Microfluidics
  • Biomedical Engineering
  • Materials Science

Background:

  • Lab-on-a-chip (LOC) and point-of-care (POC) devices require precise fluid handling.
  • External pumping systems for microfluidics are often bulky, complex, and costly.
  • Integrated pumping solutions are needed to miniaturize and simplify LOC/POC devices.

Purpose of the Study:

  • To develop a novel, integrated pumping solution for microfluidic devices.
  • To demonstrate the feasibility of an asymmetric elasto-magnetic system for fluid pumping.
  • To investigate the tuneability and reversibility of the fluid flow generated by the system.

Main Methods:

  • Design and fabrication of a monolithic elasto-magnetic pump integrated into a microfluidic device.
  • Actuation of the pump using a weak, uniform, oscillating magnetic field (3-6 mT).
  • Experimental characterization of fluid flow rate, tuneability, and viscosity dependence.

Main Results:

  • Achieved tuneable fluid flow rates up to 600 microL/h.
  • Demonstrated flow reversal by adjusting the driving frequency.
  • Confirmed successful operation with fluids of varying viscosities, with optimal frequency decreasing for higher viscosities.
  • Explained fluid flow mechanism via non-reciprocal motion of the elasto-magnetic component.

Conclusions:

  • The asymmetric elasto-magnetic system offers a novel, integrated pumping solution for microfluidic applications.
  • This technology can replace external pumping systems, leading to simpler and more compact LOC/POC devices.
  • The system's tuneable flow rate, reversibility, and viscosity adaptability make it a versatile component for microfluidic systems.