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Updated: Dec 4, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Endoscopic extrasellar skull base reconstruction using bioabsorbable plates.

Scott C Seaman¹, Mckay J Moline², Scott M Graham²

¹Department of Neurosurgery, United States of America.

American Journal of Otolaryngology

|October 25, 2020

Summary

This summary is machine-generated.

Rigid absorbable plates offer an effective solution for anterior skull base reconstruction, demonstrating no postoperative cerebrospinal fluid leaks or complications. This technique provides a customizable and bioabsorbable alternative for diverse defects.

Keywords:

Anterior skull base Ethmoid Nasoseptal flap Rigid repair Sphenoid Surgical technique

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Last Updated: Dec 4, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Area of Science:

Neurosurgery
Otolaryngology
Plastic Surgery

Background:

Anterior skull base reconstruction involves various techniques, each with unique benefits and drawbacks.
Rigid reconstruction methods may offer superior outcomes in specific patient populations.

Purpose of the Study:

To evaluate the efficacy and safety of rigid, resorbable poly (D,L) lactic acid plates for anterior skull base reconstruction.
To compare outcomes and complications with existing skull base reconstruction techniques.

Main Methods:

Retrospective review of 24 patients undergoing endoscopic extrasellar skull base reconstruction between 2012-2019.
Utilized resorbable poly (D,L) lactic acid plates (Resorb-X Sellar Wall Plate).
Collected data on demographics, surgical indications, defect characteristics, peri-operative CSF diversion, complications, and follow-up.

Main Results:

25 procedures were performed on 24 patients (mean age 53 years, mean BMI 34 kg/m²).
Indications included cerebrospinal fluid (CSF) leaks and tumor resection defects; 4 cases were revisions.
No postoperative CSF leaks, mortality, or morbidity related to the reconstruction or implant occurred.

Conclusions:

Resorb-X resorbable rigid plates are effective, customizable, and bioabsorbable for skull base reconstruction.
This technique serves as a viable alternative to previously described methods for diverse skull base defects.