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Related Experiment Video

Updated: Dec 4, 2025

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
07:21

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Multiple intra-aneurysmal WEB devices: Case discussions and operative technique.

Joseph S Hudson1, Mario Zanaty2, Jorge A Roa3

  • 1Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|October 25, 2020
PubMed
Summary

Multiple Woven Endobridge (WEB) devices can treat complex aneurysms in patients unable to take dual antiplatelet therapy (DAPT). This multi-WEB approach offers a viable alternative for challenging neurovascular cases.

Keywords:
EndovascularIntracranial aneurysmWEB

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Area of Science:

  • Neurosurgery
  • Endovascular techniques
  • Cerebrovascular disease

Background:

  • The Woven Endobridge (WEB) device is an FDA-approved endosaccular flow diverter for complex aneurysms.
  • Dual antiplatelet therapy (DAPT) is typically required post-WEB deployment.
  • Patient non-compliance with DAPT poses a challenge for endovascular aneurysm treatment.

Observation:

  • Two cases of ophthalmic segment internal carotid artery aneurysms are presented.
  • Multiple WEB devices were deployed within the aneurysm sac in each case.
  • Patients were non-compliant with standard DAPT regimens.

Findings:

  • Successful deployment of multiple WEB devices achieved flow disruption within the aneurysm sac.
  • Techniques to maintain parent vessel patency were employed.
  • The multi-WEB construct effectively treated complex aneurysms in DAPT-intolerant patients.

Implications:

  • This approach expands treatment options for complex aneurysms in patients with contraindications to DAPT.
  • Multi-WEB intra-aneurysmal constructs may be a safe and effective alternative.
  • Further research into DAPT-free WEB treatment strategies is warranted.