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Published on: June 21, 2019
Prophylactic levetiracetam-induced pancytopenia with traumatic extra-dural hematoma: Case report
Omar Bangash1, Alexandre Simonin1, Chrisovalantis Tsimiklis1
1Department of Neurosurgery, Sir Charles Gairdner Hospital (SCGH), Perth, WA, Australia.
Background:
Pancytopenia has only rarely been reported with Levetiracetam use. It is a potentially life threatening adverse effect that requires cessation of therapy.
Case Description:
We describe a case of an otherwise well thirty-two-year-old man who underwent an emergent craniotomy for evacuation of a traumatic extra-dural haematoma. Post-operatively, he developed pancytopenia which corrected with cessation of levetiracetam.
Conclusion:
This report aims to increase awareness of this rare side effect and reiterates the judicious use of prophylactic levetiracetam in brain trauma.
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