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Micronutrients: Essential Treatment for Inflammatory Arthritis?
Marina Bañuls-Mirete1, Alexis Ogdie2, Monica Guma3,4
1Department of Medicine, School of Medicine, University of California, San Diego UCSD, 9500 Gilman Dr. MC 0663, La Jolla, CA, 92093-0663, USA.
Current Rheumatology Reports
|October 26, 2020
Summary
Dietary micronutrients, including polyphenols, show anti-inflammatory effects in chronic inflammatory arthropathies. Incorporating these nutrients may improve arthritis symptoms and inflammation, potentially altering disease progression.
Area of Science:
- Nutrition Science
- Immunology
- Rheumatology
Background:
- Synovial inflammation is a hallmark of chronic arthropathies, leading to joint damage, pain, and functional decline.
- Research is exploring anti-inflammatory micronutrients found in plant-based foods and beverages.
Purpose of the Study:
- To review the anti-inflammatory effects of polyphenols and other micronutrients in patients with chronic inflammatory arthropathies.
- To examine evidence from randomized clinical trials on these dietary components.
Main Methods:
- Review of randomized clinical trials investigating micronutrient and nutrient-enriched food intake.
- Analysis of studies focusing on polyphenols and other micronutrients in chronic inflammatory arthropathies.
Main Results:
- Growing evidence suggests micronutrient intake influences synovitis pathogenesis and remission.
- Clinical trials indicate improvements in arthritis symptoms and inflammatory mediators with specific micronutrient interventions.
- Convincing evidence supports the anti-inflammatory impact of several micronutrients on arthritis.
Conclusions:
- Dietary micronutrients can positively modulate arthritis symptoms and inflammation.
- Integrating these nutrients into daily diets may alter the course of inflammatory arthritis.
- Further research is needed to establish consensus on specific nutritional recommendations for chronic synovial inflammation.
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