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2018 Lush Science Prize
1TJM Consultancy, Jaén, Spain.
Alternatives to Laboratory Animals : ATLA
|October 27, 2020
Summary
The Lush Prize supports animal-free testing by awarding significant funding to researchers and projects dedicated to replacing animal use in safety testing. This paper reviews 2018 Science Prize candidates and recent advancements in non-animal toxicity testing methods.
Area of Science:
- * Toxicology and regulatory science.
- * Development and application of New Approach Methodologies (NAMs) for chemical safety assessment.
- * Advancement of animal-free testing strategies.
Background:
- * The Lush Prize has awarded nearly £2 million since 2012 to promote alternatives to animal testing.
- * Prizes recognize advancements in Science, Lobbying, Training, Public Awareness, and support for Young Researchers.
- * A special Black Box prize was awarded in 2015 for a skin sensitization Adverse Outcome Pathway and in vitro assays.
Purpose of the Study:
- * To outline research projects considered for the 2018 Lush Science Prize.
- * To provide an overview of recent developments in animal replacement in toxicity research.
- * To highlight key scientific institutions and initiatives in the field of non-animal testing.
Main Methods:
- * Review of recent work from major scientific institutions and projects (e.g., OECD, CAAT, ECVAM, NC3Rs, Tox21, ToxCast, EU-ToxRisk).
- * Literature search for recent developments in toxicity testing research.
- * Analysis of abstracts from key conferences on animal replacement in toxicity testing held in the preceding 12 months.
Main Results:
- * Identified numerous research projects and scientific advancements in animal-free toxicity testing.
- * Documented progress in areas such as skin sensitization assays and Adverse Outcome Pathways.
- * Highlighted the growing body of work from leading global organizations in the field.
Conclusions:
- * Significant progress is being made in the development and implementation of non-animal testing methods.
- * The research reviewed demonstrates a strong commitment to replacing animal use in safety testing.
- * Continued support and recognition, such as through the Lush Prize, are crucial for accelerating these advancements.
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