Permanent pacemaker implantation associated tricuspid regurgitation

Area of Science:

• Cardiology
• Medical Devices
• Cardiac Surgery

Background:

• Tricuspid regurgitation (TR) is a common valvular heart disease.
• Permanent pacemaker (PPM) implantation is a standard procedure for various cardiac conditions.
• The impact of dual-chamber PPM on tricuspid valve function requires further investigation.

Purpose of the Study:

• To determine the prevalence of significant tricuspid regurgitation following dual-chamber permanent pacemaker implantation.
• To identify risk factors associated with the development of tricuspid regurgitation post-pacemaker implantation.

Main Methods:

• A cohort of 153 patients undergoing dual-chamber PPM implantation was studied.
• Baseline and one-month post-implantation transthoracic echocardiography were performed to assess tricuspid regurgitation.
• Logistic regression models were used to analyze associations between potential risk factors (e.g., BMI, diabetes, hypertension) and tricuspid regurgitation.

Main Results:

• Significant tricuspid regurgitation was observed in 22 (15.8%) patients after PPM implantation.
• Obesity, defined as a body mass index (BMI) >30 kg·m⁻², was significantly associated with the development of tricuspid regurgitation (OR = 32.84, p=0.04).

Conclusions:

• A substantial proportion of patients develop significant tricuspid regurgitation after dual-chamber pacemaker implantation.
• Elevated BMI (>30 kg·m⁻²) is an independent risk factor for tricuspid regurgitation in this patient population.