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Iatrogenic Takotsubo Cardiomyopathy Following Overdose Norepinephrine Administration During Percutaneous Coronary

Yen-Hsu Chen1,2, Hui-Chin Lai1,3, Wen-Lieng Lee1,3

  • 1Cardiovascular Center, Taichung Veterans General Hospital.

International Heart Journal
|October 29, 2020
PubMed

Insights

Takotsubo cardiomyopathy (TTC) can occur after catecholamine administration. This case highlights TTC development during a medical procedure, emphasizing its consideration in acute coronary syndrome-like presentations.

Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • Takotsubo cardiomyopathy (TTC) involves reversible ventricular dysfunction.
  • Catecholamines, both endogenous and exogenous, can trigger TTC.

Observation:

  • A patient developed TTC and cardiogenic shock during percutaneous coronary intervention (PCI).
  • This event was linked to inadvertent norepinephrine administration.

Findings:

  • The patient's hemodynamic status and cardiac function fully recovered within one week.
  • Recovery was achieved with hemodynamic support via an intra-aortic balloon pump, with no lasting effects.

Implications:

  • TTC should be considered in patients presenting with symptoms resembling acute coronary syndrome (ACS) after catecholamine exposure.
  • This case underscores the importance of monitoring for TTC in clinical settings involving catecholamine administration.

Keywords:
Cardiogenic shockCatecholamineStress-induced cardiomyopathy

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