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Thyroid Function Status in Elderly Male.

F Yeasmin¹, A Nessa, T A Sohan

¹Dr Farzana Yeasmin, Lecturer, Department of Physiology, Mymensingh Medical College (MMC), Mymensingh, Bangladesh;

Mymensingh Medical Journal : MMJ

|October 29, 2020

Summary

As men age, thyroid hormone levels change, leading to decreased thyroid function. This study found lower free tri-iodothyronine (FT₃) and free thyroxine (FT₄), and higher thyroid stimulating hormone (TSH) in elderly males compared to younger ones.

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Area of Science:

Endocrinology
Gerontology
Physiology

Background:

Thyroid hormone production, metabolism, and action are altered with aging.
The prevalence of thyroid dysfunction significantly increases in older populations.

Purpose of the Study:

To evaluate age-related changes in thyroid function among elderly males.
To compare thyroid function status between elderly and younger male populations.

Main Methods:

A cross-sectional study involving 140 male subjects (70 younger, 70 elderly).
Measurement of serum free tri-iodothyronine (FT₃), free thyroxine (FT₄), and thyroid stimulating hormone (TSH) using RIA.
Statistical analysis included unpaired student's t-test and Pearson's correlation coefficient.

Main Results:

Elderly males exhibited significantly lower mean serum FT₃ and FT₄ levels compared to younger males.
Elderly males showed a significantly higher mean serum TSH level than younger males.
Serum FT₃ and FT₄ levels were negatively correlated with age, while TSH was positively correlated with age.

Conclusions:

Thyroid function progressively declines with advancing age in males.
Age-related changes in thyroid hormones (FT₃, FT₄, TSH) are evident in the male population.