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Related Concept Videos

Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

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Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
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Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

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Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
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Standard Precaution01:26

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Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
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Preparedness and Phobias01:09

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Human fear responses to certain stimuli, such as darkness, heights, deep water, and blood, can often arise despite the absence of direct negative experiences. This phenomenon is rooted in evolutionary psychology, which posits that humans have developed a predisposition to fear stimuli that historically posed significant survival threats. This predisposition, known as preparedness, suggests that early humans who developed a fear of potentially dangerous entities, such as venomous snakes and...
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Controls in Experiments01:13

Controls in Experiments

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When conducting an experiment, it is crucial to have control to reduce bias and accurately measure the dependent variables. It also marks the results more reliable. Controls are elements in an experiment that have the same characteristics as the treatment groups but are not affected by the independent variable. By sorting these data into control and experimental conditions, the relationship between the dependent and independent variables can be drawn. A randomized experiment always includes a...
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PPE Use in Healthcare Settings I: Donning01:22

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Donning PPE must be completed before contact with the patient. This process protects from infectious agents. The sequence and action included in each donning are critical, and the steps must be systematic to avoid exposure to pathogens. The institutional policy also needs to be followed while donning PPE. The pre-donning preparations are gathering equipment, inspecting the PPE equipment for tears, holes, or damage, removing jewelry, removing any garments below the elbows, and tying the hair...
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Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
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Flattening the Risk: Pre-Exposure Prophylaxis for COVID-19.

Raphael B Stricker1, Melissa C Fesler1

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Summary

The COVID-19 pandemic caused millions of infections and deaths globally. This study presents a new aggressive prophylaxis strategy to mitigate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread and reduce losses.

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COVID-19SARScoronavirusprophylaxis

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Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, has resulted in over 35 million infections and one million deaths worldwide.
  • Economic and social disruptions are significant due to widespread fear and social isolation measures.
  • Resuming economic activities necessitates a medical strategy to prevent further population losses.

Purpose of the Study:

  • To propose an aggressive prophylaxis strategy to combat the SARS-CoV-2 pandemic.
  • To address the medical and public health challenges posed by COVID-19.
  • To mitigate the ongoing severe losses experienced by the global population.

Main Methods:

  • The study outlines a proactive plan for SARS-CoV-2 prophylaxis.
  • The strategy focuses on aggressive measures to control viral spread.
  • Details of the proposed plan are presented within the full study.

Main Results:

  • The current approach to managing COVID-19 has led to severe and ongoing population losses.
  • The absence of an aggressive prophylaxis strategy exacerbates the pandemic's impact.
  • The presented plan aims to provide a viable solution to reduce these losses.

Conclusions:

  • An aggressive prophylaxis strategy is crucial for mitigating the impact of SARS-CoV-2.
  • The proposed plan offers a medical perspective to counter the pandemic's devastating effects.
  • Implementing this strategy can help reduce severe losses and facilitate a safer return to normalcy.