Developing a CNT-SPE Sensing Platform Based on Green Synthesized AuNPs, Using Sargassum sp

Area of Science:

• Biomedical research
• Electrochemical sensing
• Nanotechnology

Background:

• Detection and quantification of analytes are crucial in biomedical research.
• Electrochemical sensing platforms offer advanced analytical capabilities.
• Green synthesis of nanomaterials provides sustainable alternatives.

Purpose of the Study:

• To develop a novel portable electrochemical sensing platform for glucose detection.
• To utilize green-synthesized gold nanoparticles (AuNPs) for sensor modification.
• To characterize the synthesized AuNPs and evaluate sensor performance.

Main Methods:

• Green synthesis of AuNPs from Sargassum sp.
• Characterization of AuNPs using UV-Vis, FT-IR, XRD, SEM, DLS, and zeta potential.
• Modification of carbon nanotubes-screen printed electrode (CNT-SPE) with AuNPs via drop-casting.
• Electrochemical detection of glucose using cyclic voltammetry (CV).

Main Results:

• Successfully synthesized stable, organic-capped, face-centered cubic AuNPs (80-100 nm).
• Assembled a novel portable electrochemical sensing platform for glucose.
• Demonstrated the ability to sense and measure glucose with limits of detection (LOD) of 50 μM and quantification (LOQ) of 98 μM.

Conclusions:

• The developed AuNP-modified CNT-SPE platform is effective for glucose sensing.
• Green synthesis offers a viable route for producing stable AuNPs for electrochemical applications.
• This novel sensor combination shows promise for portable and sensitive glucose monitoring in biomedical research.