Water-Splitting Based and Related Therapeutic Effects: Evolving Concepts, Progress, and Perspectives

Area of Science:

• Biomedical Engineering
• Chemical Engineering
• Materials Science

Background:

• Water-splitting is primarily researched for energy applications.
• Its significant potential in biomedical applications, particularly in disease treatment, is often overlooked.
• Recent advancements demonstrate innovative therapeutic uses for water-splitting technologies.

Purpose of the Study:

• To elucidate the principles of water-splitting applied to biomedical treatments.
• To summarize recent breakthroughs in using water-splitting for therapeutic outcomes.
• To bridge the knowledge gap between energy and biomedical applications of water-splitting.

Main Methods:

• Review of scientific literature focusing on water-splitting in medicine.
• Analysis of therapeutic mechanisms enabled by water-splitting principles.
• Synthesis of findings to highlight underreported applications.

Main Results:

• Water-splitting enables novel therapeutic strategies for cancer and other diseases.
• These methods offer advantages over conventional treatment approaches.
• The term "water-splitting" is rarely associated with these biomedical innovations.

Conclusions:

• The biomedical importance of water-splitting is significantly underestimated.
• Further research and interdisciplinary collaboration can accelerate its therapeutic development.
• This review aims to raise awareness among biomedical and energy scientists.