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The Role of PPARs in Disease

Nicole Wagner1, Kay-Dietrich Wagner1

  • 1Université Côte d'Azur, CNRS, INSERM, iBV, 06107 Nice, France.

Cells
|October 31, 2020
PubMed
Summary

Peroxisome proliferator-activated receptors (PPARs) regulate metabolism and cell functions. This issue explores recent advances in PPARs, highlighting therapeutic potential for metabolic and cardiovascular diseases, despite controversies surrounding PPARβ/δ.

Keywords:
Alzheimer’s disease (AD)addictionadipogenesisalcoholanimal modelscancercellular metabolismfibrosishuman studieshypertrophic obesityinflammationinsulin-resistancekidneyligandslipidomicsnicotinenon-alcoholic fatty liver disease (NAFLD)non-alcoholic steatohepatitis (NASH)opioidsperoxisome proliferator-activated receptor-γ coactivator-1αperoxisome proliferator-activated receptors (PPARs)pharmacologyproliferationpsychostimulantstoxicologytumor angiogenesisvascular

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