Related Experiment Video
Updated: Dec 3, 2025

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
Published on: November 1, 2024
Inflammatory choroiditis and papillitis from Crohn's disease in a child
David A Kilgore1, Alice W Behrens1, Mohammad Z Siddiqui1
1Jones Eye Institute, Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Insights
A young boy experienced vision loss due to inflammatory eye conditions linked to Crohn's disease. Intravitreal corticosteroids effectively treated his optic nerve and macular swelling.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Inflammatory Bowel Disease
Background:
- Crohn's disease is a chronic inflammatory condition that can affect various parts of the body, including the eyes.
- Ocular manifestations of Crohn's disease, though rare, can lead to significant visual impairment.
Observation:
- A 5-year-old boy presented with subacute, painless visual loss in his left eye.
- Clinical examination revealed optic disk edema, macular edema, and choroidal thickening.
Findings:
- The patient was diagnosed with inflammatory papillitis and choroiditis secondary to Crohn's disease.
- Initial treatment with anti-vascular endothelial growth factor (VEGF) injections showed minimal improvement in ocular edema.
- Intravitreal corticosteroids resulted in significant resolution of the disk and macular edema.
Implications:
- This case highlights a rare but serious ocular complication of pediatric Crohn's disease.
- Early diagnosis and prompt treatment with corticosteroids are crucial for managing inflammatory eye conditions associated with Crohn's disease.
- Ophthalmologists should consider inflammatory eye disease in children with Crohn's disease presenting with visual disturbances.
Abstract:
A 5-year-old boy had subacute painless visual loss in his left eye with disk edema, macular edema, and choroidal thickening. He was subsequently diagnosed with inflammatory papillitis and choroiditis from Crohn's disease. The disk and macular edema responded minimally to antivascular endothelial growth factor injections but significantly to intravitreal corticosteroids.
More Related Videos
Related Concept Videos
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...

