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Canine Protein Losing Enteropathies and Systemic Complications
Karin Allenspach1, Chelsea Iennarella-Servantez1
1Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, 1809 South Riverside Drive, Ames, IA 50010, USA.
The Veterinary Clinics of North America. Small Animal Practice
|November 2, 2020
Summary
Canine protein-losing enteropathies are difficult to manage, with a 50% survival rate. Investigating systemic issues like hypercoagulability and nutrient deficiencies can improve outcomes for affected dogs.
Area of Science:
- Veterinary Medicine
- Gastroenterology
- Internal Medicine
Background:
- Canine protein-losing enteropathies (PLE) are common and challenging gastrointestinal diseases in dogs.
- Current management strategies offer limited long-term success, with approximately 50% of affected dogs surviving.
- Identifying prognostic factors is crucial for improving patient outcomes.
Purpose of the Study:
- To review recent findings on prognostic factors influencing the outcome of canine protein-losing enteropathies.
- To highlight the importance of investigating specific systemic complications in severely affected cases.
Main Methods:
- Review of recent scientific literature and studies on canine protein-losing enteropathies.
- Analysis of identified prognostic factors and their impact on disease outcome.
- Emphasis on systemic complications relevant to clinical management.
Main Results:
- Systemic complications significantly impact the prognosis of canine protein-losing enteropathies.
- Hypercoagulability, vitamin D3 deficiency, and tryptophan deficiency are key factors to consider.
- Early identification and management of these complications are associated with better outcomes.
Conclusions:
- Prognostic factors, particularly systemic complications, are critical for managing canine protein-losing enteropathies.
- Investigating hypercoagulability, vitamin D3 deficiency, and tryptophan deficiency in severely affected dogs is recommended.
- Targeted management of these systemic issues can potentially maximize long-term survival rates in dogs with PLE.
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