Photodynamic Therapy in Ocular Oncology.
Mehdi Mazloumi1, Lauren A Dalvin2, Seyed-Hossein Abtahi3
1Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, USA.
Journal of Ophthalmic & Vision Research
|November 2, 2020
Summary
Photodynamic therapy (PDT) is increasingly used for ocular oncology, managing both benign and malignant intraocular tumors. This review covers PDT applications for conditions like choroidal hemangioma and melanoma.
Area of Science:
- Ocular Oncology
- Photodynamic Therapy
Background:
- Photodynamic therapy (PDT) has gained prominence in ocular oncology over the last 20 years.
- Its application extends to managing various intraocular tumors.
Purpose of the Study:
- To review the role and application of PDT in managing intraocular tumors.
- To discuss PDT's efficacy in both benign and malignant ocular conditions.
Main Methods:
- Literature review.
- Analysis of clinical experience with PDT for intraocular tumors.
Main Results:
- PDT is applied to benign tumors: circumscribed choroidal hemangioma, choroidal osteoma, retinal astrocytoma, retinal capillary hemangioma, and retinal vasoproliferative tumor.
- PDT is assessed for malignant tumors: choroidal melanoma and choroidal metastasis.
Conclusions:
- PDT is a valuable therapeutic option for a range of intraocular tumors.
- Further evaluation of PDT in ocular oncology is warranted.
