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Updated: Dec 2, 2025

Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects
Published on: February 12, 2021
Covid-19 positivity affects outcome of cardiac surgical patients
Anastasia Katsiampoura1, Cesar Perozo1, Andreas Varkaris2
1Department of Anesthesiology, St Elizabeth's Medical Center, Tufts Medical School, Boston, Massachusetts.
Insights
Patients undergoing urgent cardiothoracic surgery with COVID-19 have very high mortality. Prevention and preoperative screening are crucial to prevent nosocomial spread of the coronavirus disease 2019 (COVID-19).
Area of Science:
- Cardiothoracic Surgery
- Infectious Diseases
- Critical Care Medicine
Background:
- Describes clinical presentation, laboratory findings, and outcomes of four patients requiring urgent cardiothoracic intervention who tested positive for COVID-19.
- Highlights the critical intersection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and complex surgical procedures.
Observation:
- Patients undergoing surgery generally had low Society of Thoracic Surgeons scores and uneventful operative times.
- Despite surgical factors, mortality rates were notably high, predominantly attributed to the viral syndrome.
Findings:
- Laboratory markers associated with COVID-19 severity in the general population also proved prognostic in this surgical cohort.
- The study identified a strong correlation between viral syndrome severity and patient outcomes.
Implications:
- Emphasizes the critical need for robust prevention strategies and preoperative screening protocols to mitigate nosocomial spread of COVID-19 in surgical settings.
- Suggests that early identification and management of COVID-19 related complications are paramount for improving survival rates in these high-risk patients.
Introduction:
In this report we describe the clinical presentation, laboratory findings and outcomes of four patients that were referred for urgent cardiothoracic intervention and tested positive for COVID-19.
Methods:
The St. Elizabeth's Medical Center Institutional Review Board exempted the study from review (waived review). In each case, verbal informed consent was obtained by the study participant or health care proxy.
Results:
The majority of the patients undergoing surgery had low Society of Thoracic Surgeons score and uneventful operating time. The mortality was very high and driven primarily by the viral syndrome. Laboratory markers that have been associated with disease severity in the general population were also prognostic in our population.
Conclusion:
Our study shows that these patients have very high mortality, whereas prevention and preoperative screening is required in preventing nosocomial spreading of the disease.
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