Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Laser-Emitting Droplet Assay for Enzymatic Evaluation Applications.

ACS nano·2026
Same author

High-Performance Flexible Ultraviolet Phototransistor Based on an AlGaN/GaN Heterojunction Membrane.

ACS applied materials & interfaces·2026
Same author

Broadband Nanocavity Imaging with Machine Vision for Multiplex miRNA Assays.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Cavity-Enhanced Catalytic Array for Monitoring Spontaneous Catalytic Dynamics and Applications.

Nano letters·2026
Same author

A Functional Air-Bubble Microlaser for Screening Photothermal Agents in Tumor Multicellular Model.

Nano letters·2026
Same author

Magnetically Driven Lasing Microrobots for Precise Photodynamic Therapy.

ACS nano·2026
Same journal

Engineered Young Brown Adipose Tissue-Derived Exosomes Alleviate Radiation-Induced Lung Injury by Promoting G Protein-Coupled Receptor 183 Ubiquitination.

ACS nano·2026
Same journal

Pore Geometry-Driven Capture of Trace Aromatic Volatile Organic Compounds in Al-Based MOFs.

ACS nano·2026
Same journal

Dual-Bridged Porphyrin-Based Covalent Organic Framework with Integrated Specific Fluorescent Recognition and Cooperative Adsorption Capabilities.

ACS nano·2026
Same journal

Split-Gate Memtransistors for Energy-Efficient Adaptive Reinforcement Learning.

ACS nano·2026
Same journal

Interface Coordination Nucleation of Copper Nanoclusters on Covalent Organic Frameworks for Electrocatalytic Ammonia Synthesis.

ACS nano·2026
Same journal

High-Performance Near-Infrared Quantum Emission from Color Centers in hBN.

ACS nano·2026
See all related articles

Related Experiment Video

Updated: Dec 2, 2025

Laser-induced Forward Transfer for Flip-chip Packaging of Single Dies
08:21

Laser-induced Forward Transfer for Flip-chip Packaging of Single Dies

Published on: March 20, 2015

12.7K

DNA Self-Switchable Microlaser.

Yifan Zhang1, Xuerui Gong1, Zhiyi Yuan1

  • 1School of Electrical and Electronic Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore.

ACS Nano
|November 2, 2020
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel switchable laser controlled by DNA. This biointerface technology allows for reversible wavelength tuning, paving the way for programmable photonic devices.

Keywords:
DNAliquid crystalsmicrocavityswitchable biointerfacetunable microlaser

More Related Videos

Probing Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices via Laser Flash Photolysis of Photoactivatable Nicotine
10:48

Probing Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices via Laser Flash Photolysis of Photoactivatable Nicotine

Published on: January 25, 2019

9.6K
Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points
09:30

Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points

Published on: March 2, 2011

16.0K

Related Experiment Videos

Last Updated: Dec 2, 2025

Laser-induced Forward Transfer for Flip-chip Packaging of Single Dies
08:21

Laser-induced Forward Transfer for Flip-chip Packaging of Single Dies

Published on: March 20, 2015

12.7K
Probing Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices via Laser Flash Photolysis of Photoactivatable Nicotine
10:48

Probing Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices via Laser Flash Photolysis of Photoactivatable Nicotine

Published on: January 25, 2019

9.6K
Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points
09:30

Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points

Published on: March 2, 2011

16.0K

Area of Science:

  • Optics and Photonics
  • Biotechnology
  • Materials Science

Background:

  • Switchable microlasers are crucial for integrated photonics and controlling light-matter interactions.
  • Stimuli-responsive biointerfaces offer advanced functionalities for nanoscale optical tailoring.
  • Biological recognition for laser emission switching, especially with reversibility and broad spectral tunability, remains an underexplored area.

Purpose of the Study:

  • To demonstrate a self-switchable laser utilizing a biointerface for biological recognition-based control.
  • To achieve reversible and broadly tunable laser emission by exploiting DNA conformation changes.
  • To explore the potential of biomolecules in developing programmable photonic devices.

Main Methods:

  • Fabrication of a Fabry-Perot microcavity incorporating a dye-doped liquid crystal matrix.
  • Integration of label-free DNA molecules at the biointerface to act as a switching mechanism.
  • Utilizing DNA conformation changes induced by varying concentrations to alter liquid crystal orientation and control laser emission.

Main Results:

  • Demonstrated laser emission switching among different wavelengths triggered by DNA conformation changes.
  • Observed distinct temporal switching patterns of lasing wavelengths and intensities based on single-stranded DNA concentration.
  • Achieved reversibility of lasing wavelength through DNA hybridization with complementary sequences.

Conclusions:

  • The study presents a milestone in biologically controlled lasers, leveraging DNA-liquid crystal biointerfaces.
  • DNA conformation changes effectively control laser emission switching and wavelength tuning.
  • This work opens avenues for sub-nanoscale programmable photonic devices utilizing biomolecular self-recognition.