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Updated: Dec 2, 2025

Dissection Techniques and Histological Sampling of the Heart in Large Animal Models for Cardiovascular Diseases
Published on: June 16, 2022
Overview of the Whole Heart and Heart Chamber Segmentation Methods.
Marija Habijan1, Danilo Babin2, Irena Galić3
1Faculty of Electrical Engineering, Computer Science and Information Technology Osijek, Kneza Trpimira 2b, 31000, Osijek, Croatia. marija.habijan@ferit.hr.
This review overviews cardiac image segmentation methods for cardiovascular disease (CVD) research. It compares edge-based, model-fitting, and deep learning approaches across CT, MRI, and echocardiography, highlighting challenges and performance factors.
Area of Science:
- Medical Imaging
- Cardiovascular Research
- Image Processing
Background:
- Cardiovascular disease (CVD) research prioritizes heart and vessel health.
- Advanced imaging techniques enhance understanding of disease physiology and progression.
- Cardiac image processing aims for comprehensive cardiac analysis, but modality differences pose segmentation challenges.
Purpose of the Study:
- To critically review segmentation methods for the whole heart, bi-ventricles, and left atrium.
- To compare segmentation techniques across Computed Tomography (CT), Magnetic Resonance Imaging (MRI), and echocardiography (echo).
- To summarize segmentation challenges, classify contributions, and evaluate method performance and accuracy.
Main Methods:
- Methods are classified into edge-based, model-fitting, and machine/deep learning approaches.
- Segmentation methods are further categorized by the targeted cardiac structure.
- A critical review assesses the performance and accuracy of various segmentation techniques.
Main Results:
- Edge-based methods offer semi-automatic control for physicians.
- Model-fitting methods are robust to image quality variations but require prior knowledge.
- Deep learning methods show high performance with sufficient, accurate training data.
Conclusions:
- The choice of segmentation algorithm depends on imaging modality and desired level of automation.
- Each segmentation approach (edge-based, model-fitting, deep learning) has distinct advantages and limitations.
- Future research should focus on improving the robustness and data efficiency of deep learning cardiac segmentation.
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