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Related Experiment Video

Updated: Dec 2, 2025

Patterning Bioactive Proteins or Peptides on Hydrogel Using Photochemistry for Biological Applications
09:19

Patterning Bioactive Proteins or Peptides on Hydrogel Using Photochemistry for Biological Applications

Published on: September 15, 2017

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Bioinspired living structural color hydrogels.

Fanfan Fu1, Luoran Shang1, Zhuoyue Chen1

  • 1State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.

Science Robotics
|November 3, 2020
PubMed
Summary
This summary is machine-generated.

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Scientists created a living structural color material inspired by chameleons. Engineered heart cells on hydrogel films enable autonomous color changes, paving the way for biohybrid robots and advanced drug screening platforms.

Area of Science:

  • Biohybrid Materials Science
  • Soft Robotics
  • Biomedical Engineering

Background:

  • Structural color materials mimic natural iridescence but synthetic versions require external stimuli.
  • Autonomous color regulation is common in nature (e.g., chameleons) but challenging to replicate artificially.
  • Existing artificial structural color materials have limitations due to their dependence on external triggers.

Purpose of the Study:

  • To develop a novel structural color material with autonomous regulation capabilities.
  • To mimic the color-changing mechanisms observed in natural organisms like chameleons.
  • To explore applications in biohybrid robotics, living materials, and microfluidic devices.

Main Methods:

  • Assembled engineered cardiomyocyte tissues onto synthetic inverse opal hydrogel films.

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Last Updated: Dec 2, 2025

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  • Utilized the natural elongation and contraction cycles of beating cardiomyocytes.
  • Observed changes in the hydrogel's inverse opal structure and corresponding shifts in photonic band gap and structural colors.

    • Main Results:

    • Demonstrated a biohybrid structural color material with autonomic regulation.
    • Created dynamic living materials, including 2D patterns and 3D Morpho butterfly models.
    • Developed a "heart-on-a-chip" platform for biological research and drug screening using microfluidics.

    Conclusions:

    • The biohybrid approach provides intrinsic color-sensing feedback for system modification.
    • This technology enables the creation of intelligent actuators and soft robotic devices.
    • The developed living structural color hydrogels offer versatile applications in advanced material design and biological research.