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Related Experiment Videos

Natural family planning.

J B Brown1, L F Blackwell, J J Billings

  • 1Department of Obstetrics and Gynecology, University of Melbourne, Victoria, Australia.

American Journal of Obstetrics and Gynecology
|October 1, 1987
PubMed
Summary

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Accurately identifying a woman's fertile window is key for natural family planning. New enzyme immunoassays for home use can reliably detect urinary estrogen and pregnanediol glucuronides, aiding fertility awareness.

Area of Science:

  • Reproductive Endocrinology
  • Biochemistry
  • Family Planning

Background:

  • Natural family planning (NFP) relies on accurately identifying the fertile window, typically around 7 days per menstrual cycle.
  • Traditional NFP methods like cervical mucus monitoring and basal body temperature tracking have limitations and can lead to failures.
  • Hormonal fluctuations during the menstrual cycle, specifically ovarian and pituitary hormones, offer reliable indicators of fertility.

Purpose of the Study:

  • To develop and evaluate enzyme immunoassays for home-based measurement of urinary estrogen and pregnanediol glucuronides.
  • To provide a more accurate and reliable method for identifying the fertile period compared to existing symptomatic markers.

Main Methods:

  • Development of enzyme immunoassays for urinary estrogen and pregnanediol glucuronides.
Keywords:
AntibodiesAntigen-antibody ReactionsBasal Body Temperature MethodBehaviorBiologyBody Temperature--changesCervical Mucus MethodContraceptionEconomic FactorsEvaluationExaminations And DiagnosesFamily PlanningFamily Planning, Behavioral MethodsFertile PeriodImmunityImmunologic FactorsLaboratory Examinations And DiagnosesLaboratory ProceduresMotivationNatural Family PlanningOvulation DetectionPhysiologyPsychological FactorsReproductionTechnology--changes

Related Experiment Videos

  • Assays designed for home use with timed urine specimens.
  • Early versions used visual estimation of enzyme reaction rates; later versions incorporated a photoelectronic rate meter for improved accuracy.

    • Main Results:

    • Urinary estrogen and pregnanediol measurements provide reliable data on the fertile period's onset, peak, and end.
    • The developed enzyme immunoassays enable accurate home-based monitoring of these fertility indicators.
    • Technological advancements have improved the precision of the assay measurements.

    Conclusions:

    • Enzyme immunoassays for urinary estrogen and pregnanediol glucuronides offer a reliable tool for fertility awareness.
    • The primary challenge for widespread adoption is user motivation for consistent daily monitoring.
    • This technology has the potential to improve the effectiveness and reduce the cost of natural family planning.