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SARS-CoV-2 (COVID-19) and the Endocrine System
Michelle D Lundholm1, Caroline Poku2, Nicholas Emanuele2,3
1Department of Internal Medicine, Loyola University Medical Center, Maywood, Illinois.
Journal of the Endocrine Society
|November 4, 2020
Summary
This review summarizes the widespread effects of SARS-CoV-2 (COVID-19) on the endocrine system, including diabetes, pituitary, adrenal, thyroid, bone, and gonadal function. Long-term impacts of COVID-19 on endocrine health require further investigation.
Area of Science:
- Endocrinology
- Infectious Diseases
- Systemic Manifestations of Viral Illness
Background:
- SARS-CoV-2 (COVID-19) infection can lead to moderate to severe illness in approximately 15% of cases.
- COVID-19 presents with diverse clinical manifestations affecting multiple organ systems.
- Emerging evidence indicates significant impact on the endocrine system.
Purpose of the Study:
- To review the current understanding of COVID-19's impact on endocrine pathophysiology.
- To discuss the management of endocrine disorders in COVID-19 patients.
- To highlight areas for future research regarding long-term endocrine sequelae.
Main Methods:
- Literature review of existing studies on COVID-19 and endocrine function.
- Synthesis of findings on diabetes, pituitary, adrenal, thyroid, bone, and gonadal health.
- Analysis of current management strategies for endocrine complications.
Main Results:
- COVID-19 affects diabetes pathophysiology and management in both outpatient and inpatient settings.
- The virus impacts pituitary, adrenal, thyroid, bone, and gonadal functions.
- Data on the long-term endocrine effects of COVID-19 are still developing.
Conclusions:
- COVID-19 has profound and widespread effects on the endocrine system.
- Understanding and managing these endocrine manifestations is crucial for patient care.
- Further research is essential to elucidate the long-term consequences of COVID-19 on endocrine health.
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