Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Platelet transfusion. Current techniques, remaining problems, and future prospects.

J H Herman1, H T Kamel

  • 1American Red Cross Blood Services, Penn-Jersey Region, Philadelphia, PA 19103.

The American Journal of Pediatric Hematology/Oncology
|January 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lack of effect of donor-recipient ABO mismatching on outcome following allogeneic hematopoietic stem cell transplantation.

Bone marrow transplantation·2006
Same author

Prevalence of somatic small fiber neuropathy in obesity.

International journal of obesity (2005)·2006
Same author

Economic consequences of alterations in platelet transfusion dose: analysis of a prospective, randomized, double-blind trial.

Transfusion·2001
Same author

Congenital myasthenic syndrome with sleep hypoventilation.

Muscle & nerve·2000
Same author

Considerations in the selection of a platelet component: apheresis versus whole blood-derived.

Transfusion medicine reviews·1999
Same author

Clinical consequences of alterations in platelet transfusion dose: a prospective, randomized, double-blind trial.

Transfusion·1999
Same journal

Transient abnormal myelopoiesis in Down's syndrome neonates.

The American journal of pediatric hematology/oncology·1994
Same journal

Secondary acute promyelocytic leukemia in a child treated with epipodophyllotoxins.

The American journal of pediatric hematology/oncology·1994
Same journal

Maternal malignancy involving the products of conception: a report of malignant melanoma and medulloblastoma.

The American journal of pediatric hematology/oncology·1994
Same journal

Sphenoid sinus involvement in neuroblastoma.

The American journal of pediatric hematology/oncology·1994
Same journal

Transient lupus anticoagulant associated with prothrombin deficiency: unusual cause of bleeding in a 5-year-old girl.

The American journal of pediatric hematology/oncology·1994
Same journal

Disseminated histoplasmosis: a cause of infection-associated hemophagocytic syndrome.

The American journal of pediatric hematology/oncology·1994
See all related articles

Platelet transfusions effectively manage bleeding in thrombocytopenia. Evaluating transfusion effectiveness and managing alloimmunization are key for optimal patient outcomes.

Area of Science:

  • Hematology
  • Transfusion Medicine

Background:

  • Platelet transfusions are increasingly used to control bleeding in patients with low platelet counts or dysfunction.
  • Assessing transfusion needs relies on platelet counts, bleeding times, and clinical evaluation.

Purpose of the Study:

  • To review current practices and challenges in platelet transfusion therapy.
  • To discuss complications, product types, and effectiveness evaluation.
  • To explore strategies for managing platelet transfusion refractoriness and alloimmunization.

Main Methods:

  • Review of current literature and clinical guidelines on platelet transfusion.
  • Analysis of platelet products, including random donor and single-donor apheresis concentrates.
  • Discussion of methods for evaluating transfusion effectiveness and diagnosing alloimmunization.

Related Experiment Videos

Main Results:

  • Random donor platelet units often suffice for transfusion needs.
  • Platelet transfusion complications are similar to red cell transfusions, with added concerns.
  • Alloimmunization to histocompatibility antigens is a common cause of refractoriness to random donor platelets.

Conclusions:

  • Effective platelet transfusion requires proper evaluation of effectiveness to guide future dosing and frequency.
  • Managing alloimmunization and refractoriness necessitates advanced diagnostic and therapeutic strategies.
  • In vitro tests for platelet antibodies are under evaluation for selecting compatible platelets.