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Implications of Omitting Sentinel Lymph Node Biopsy in Patients Older Than 70 Years

Ko Un Park1, Jose G Bazan2

  • 1Division of Surgical Oncology, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus.

JAMA Surgery
|November 4, 2020
PubMed
Abstract

No abstract available in PubMed .

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
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