Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sexually Transmitted Infections01:26

Sexually Transmitted Infections

652
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
652
Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents01:24

Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents

1.1K
In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
1.1K
Peptic Ulcer Disease II: Pathophysiology01:28

Peptic Ulcer Disease II: Pathophysiology

1.5K
Peptic Ulcer Disease (PUD) is characterized by the development of ulcers in the stomach or duodenal mucosa. Its pathophysiology is complex, involving a balance between damaging and protective elements.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
1.5K
Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

579
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
579
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

380
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
380
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

3.7K
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
3.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Eschar: a small lesion with major diagnostic significance in scrub typhus.

QJM : monthly journal of the Association of Physicians·2026
Same author

Congenital multifocal alopecia in a young girl.

Paediatrics & child health·2026
Same author

Childhood leprosy: a current appraisal.

Clinical and experimental dermatology·2026
Same author

Kaposi's varicelliform eruption.

QJM : monthly journal of the Association of Physicians·2025
Same author

Metabolic syndrome and pigmentation: a review of the connecting link.

Clinical and experimental dermatology·2025
Same author

miRNA: The Next Frontier in Dermatology Research and Therapeutics.

Indian journal of dermatology·2024

Related Experiment Video

Updated: Dec 2, 2025

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
07:27

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK

Published on: December 18, 2012

12.3K

Recurrent Genital Ulcers.

Dibyendu Bikash Bhanja1, Abheek Sil1, Avik Panigrahi1

  • 1Department of Dermatology, Venereology, and Leprosy, R.G.Kar Medical College, Kolkata, West Bengal, India.

Urology
|November 5, 2020
PubMed
Summary
This summary is machine-generated.

Papulonecrotic tuberculid is a skin reaction to Mycobacterium tuberculosis. This rare condition, typically on the body, can manifest on the glans penis, causing ulcerated papules and scarring.

More Related Videos

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
08:53

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

6.6K
Isolation of Lymphocytes from Mouse Genital Tract Mucosa
04:46

Isolation of Lymphocytes from Mouse Genital Tract Mucosa

Published on: September 3, 2012

14.7K

Related Experiment Videos

Last Updated: Dec 2, 2025

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
07:27

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK

Published on: December 18, 2012

12.3K
Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
08:53

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

6.6K
Isolation of Lymphocytes from Mouse Genital Tract Mucosa
04:46

Isolation of Lymphocytes from Mouse Genital Tract Mucosa

Published on: September 3, 2012

14.7K

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Immunology

Background:

  • Papulonecrotic tuberculid is a rare cutaneous manifestation of tuberculosis.
  • It results from a hypersensitivity reaction to Mycobacterium tuberculosis.
  • Dissemination occurs via hematogenous spread from an internal tuberculous focus.

Observation:

  • Characterized by recurrent eruptions of asymptomatic, dusky red papules.
  • Lesions progress to ulceration and crusting.
  • Healing occurs over weeks, leaving varioliform scars.

Findings:

  • While typically affecting extragenital sites, isolated glans penis involvement is exceptionally rare.
  • This presentation highlights the diverse clinical spectrum of cutaneous tuberculosis.
  • Diagnosis requires high clinical suspicion and correlation with microbiological or histological evidence of tuberculosis.

Implications:

  • Understanding this rare presentation is crucial for accurate diagnosis and management of genitourinary tuberculosis.
  • Early recognition can prevent complications and facilitate timely treatment of the underlying infection.
  • Highlights the importance of considering systemic infections in dermatological diagnoses.