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Updated: Dec 2, 2025

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
Published on: October 6, 2023
HYGIENIC SUBSTANTIATION OF NECESSITY FOR MONITORING IN THE ENVIRONMENTAL OBJECTS OF SDHI FUNGICIDES CONSIDERING THEIR
Anna M Antonenko1, Bohdan І Shpak2, Оlena P Vavrinevych1
1BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.
Objective:
The aim: Was hygienic substantiation of necessity for monitoring in the environmental objects of SDHI fungicides considering their possible impact on the thyroid gland.
Patients And Methods:
Materials and methods: To test the proposed selection criteria for hygienic monitoring of pesticides that affect the thyroid gland, we evaluated 4 new SDHI fungicides from the chemical class of pyrazolecarboxamides (isopyrazam, pentiopyrad, sedaxan, fluxapyroxad).
Results:
Results: Based on the results obtained, all studied compounds are assigned to the second pesticide group, hygienic monitoring of which is desirable but not required. This is due, on the one hand, to their low toxicity, to the other, to low environmental sustainability.
Conclusion:
Conclusions: It was shown, that compared to other classes of pesticides, the studied are much less dangerous in terms of groundwater contamination.
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